Prothena Plc Stock Analysis

PRTA Stock  USD 8.90  0.09  1.02%   
Below is the normalized historical share price chart for Prothena plc extending back to December 21, 2012. This chart has been adjusted for all splits and dividends and is plotted against all major global economic recessions. As of today, the current price of Prothena Plc stands at 8.90, as last reported on the 2nd of February, with the highest price reaching 9.07 and the lowest price hitting 8.65 during the day.
IPO Date
21st of December 2012
200 Day MA
8.4378
50 Day MA
9.7872
Beta
(0.1)
 
Yuan Drop
 
Covid
 
Interest Hikes
Prothena plc holds a debt-to-equity ratio of 0.023. At present, Prothena Plc's Long Term Debt is projected to increase significantly based on the last few years of reporting. The current year's Net Debt To EBITDA is expected to grow to 6.72, whereas Net Debt is forecasted to decline to (435.2 M). With a high degree of financial leverage come high-interest payments, which usually reduce Prothena Plc's Earnings Per Share (EPS).

Asset vs Debt

Equity vs Debt

Prothena Plc's liquidity is one of the most fundamental aspects of both its future profitability and its ability to meet different types of ongoing financial obligations. Prothena Plc's cash, liquid assets, total liabilities, and shareholder equity can be utilized to evaluate how much leverage the Company is using to sustain its current operations. For traders, higher-leverage indicators usually imply a higher risk to shareholders. In addition, it helps Prothena Stock's retail investors understand whether an upcoming fall or rise in the market will negatively affect Prothena Plc's stakeholders.
For most companies, including Prothena Plc, marketable securities, inventories, and receivables are the most common assets that could be converted to cash. However, for Prothena plc, the most critical issue when managing liquidity is ensuring that current assets are properly aligned with current liabilities. If they are not, Prothena Plc's management will need to obtain alternative financing to ensure there are always enough cash equivalents on the balance sheet to meet obligations.
Price Book
1.6067
Enterprise Value Ebitda
(3.58)
Price Sales
40.2378
Shares Float
43.4 M
Wall Street Target Price
20.3333
At present, Prothena Plc's Other Stockholder Equity is projected to increase significantly based on the last few years of reporting. The current year's Stock Based Compensation is expected to grow to about 55.5 M, whereas Common Stock Shares Outstanding is forecasted to decline to about 36.6 M. . The current year's Price Earnings To Growth Ratio is expected to grow to 0.41, whereas Price To Sales Ratio is forecasted to decline to 6.02.
Prothena plc is undervalued with Real Value of 11.86 and Target Price of 20.33. The main objective of Prothena Plc stock analysis is to determine its intrinsic value, which is an estimate of what Prothena plc is worth, separate from its market price. There are two main types of Prothena Plc's stock analysis: fundamental analysis and technical analysis.
The Prothena Plc stock is traded in the USA on NASDAQ Exchange, with the market opening at 09:30:00 and closing at 16:00:00 every Mon,Tue,Wed,Thu,Fri except for officially observed holidays in the USA. Here, you can get updates on important government artifacts, including earning estimates, SEC corporate filings, announcements, and Prothena Plc's ongoing operational relationships across important fundamental and technical indicators.
Check out Your Equity Center to better understand how to build diversified portfolios, which includes a position in Prothena plc. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in main economic indicators.
For information on how to trade Prothena Stock refer to our How to Trade Prothena Stock guide.

Prothena Stock Analysis Notes

About 19.0% of the company outstanding shares are owned by corporate insiders. The company has price-to-book ratio of 1.61. Typically companies with comparable Price to Book (P/B) are able to outperform the market in the long run. Prothena plc has Price/Earnings To Growth (PEG) ratio of 0.8. The entity recorded a loss per share of 5.2. The firm had not issued any dividends in recent years. Prothena Corporation plc, a late-stage clinical company, focuses on discovery and development of novel therapies for life-threatening diseases in the United States. The company was founded in 2012 and is based in Dublin, Ireland. Prothena Corp operates under Biotechnology classification in the United States and is traded on NASDAQ Exchange. It employs 82 people. To find out more about Prothena plc contact the company at 353 1 236 2500 or learn more at https://www.prothena.com.

Prothena Plc Quarterly Total Revenue

2.42 Million

Prothena plc Investment Alerts

Many investors view ongoing market volatility as an opportunity to purchase more stocks at a favorable price or short it to generate a bearish trend profit opportunity. If you are one of those investors, make sure you clearly understand the position you are entering. Prothena Plc's investment alerts are automatically generated signals that are significant enough to either complement your investing judgment regarding Prothena plc or challenge it. These alerts can help you understand what you are buying and avoid costly mistakes.
Prothena plc generated a negative expected return over the last 90 days
The company reported the previous year's revenue of 135.16 M. Net Loss for the year was (122.31 M) with loss before overhead, payroll, taxes, and interest of (158.65 M).
Prothena plc currently holds about 508.8 M in cash with (150.05 M) of positive cash flow from operations. This results in cash-per-share (CPS) ratio of 10.84, which can makes it an attractive takeover target, given it will continue generating positive cash flow.
Prothena plc has a poor financial position based on the latest SEC disclosures
Over 80.0% of the company shares are owned by institutional investors
Latest headline from news.google.com: Prothena Share Price Crosses Above 50 Day Moving Average - Heres Why - MarketBeat

Prothena Largest EPS Surprises

Earnings surprises can significantly impact Prothena Plc's stock price both in the short term and over time. Negative earnings surprises usually result in a price decline. However, it has been seen that positive earnings surprises lead to an immediate rise in a stock's price and a gradual increase over time. This is why we often hear news about some companies beating earning projections. Financial analysts spend a large amount of time predicting earnings per share (EPS) along with other important future indicators. Many analysts use forecasting models, management guidance, and additional fundamental information to derive an EPS estimate.
Reported
Fiscal Date
Estimated EPS
Reported EPS
Surprise
2020-02-12
2019-12-31-0.6-0.540.0610 
2015-11-02
2015-09-30-0.66-0.73-0.0710 
2022-05-05
2022-03-31-0.68-0.78-0.114 
View All Earnings Estimates

Prothena Plc Environmental, Social, and Governance (ESG) Scores

Prothena Plc's ESG score is a quantitative measure that evaluates Prothena Plc's performance and commitment regarding environmental, social, and governance (ESG) factors. These scores are becoming increasingly crucial in investment decision-making processes, providing insights into non-financial aspects of Prothena Plc's operations that may have significant financial implications and affect Prothena Plc's stock price as well as guide investors towards more socially responsible investments.

Prothena Stock Institutional Investors

Shares
Geode Capital Management, Llc2025-06-30
933.4 K
Jacobs Levy Equity Management, Inc.2025-06-30
693.2 K
Balyasny Asset Management Llc2025-06-30
575.8 K
Trexquant Investment Lp2025-06-30
552.8 K
Goldman Sachs Group Inc2025-06-30
528.3 K
Cubist Systematic Strategies, Llc2025-06-30
501.8 K
Rock Springs Capital Management Lp2025-06-30
492.6 K
Granahan Investment Management Inc..2025-06-30
461.1 K
Birchview Capital, Lp2025-06-30
451 K
Fmr Inc2025-06-30
7.9 M
Blackrock Inc2025-06-30
3.9 M
Note, although Prothena Plc's institutional investors appear to be way more sophisticated than retail investors, it remains unclear if professional active investment managers can reliably enhance risk-adjusted returns by an amount that exceeds fees and expenses.

Prothena Market Capitalization

The company currently falls under 'Small-Cap' category with a current market capitalization of 474.24 M.

Prothena Profitablity

Last ReportedProjected for Next Year
Return On Tangible Assets(0.20)(0.21)
Return On Capital Employed(0.28)(0.29)
Return On Assets(0.20)(0.21)
Return On Equity(0.23)(0.24)

Management Efficiency

Prothena plc has return on total asset (ROA) of (0.2931) % which means that it has lost $0.2931 on every $100 spent on assets. This is way below average. Similarly, it shows a return on stockholder's equity (ROE) of (0.6763) %, meaning that it created substantial loss on money invested by shareholders. Prothena Plc's management efficiency ratios could be used to measure how well Prothena Plc manages its routine affairs as well as how well it operates its assets and liabilities. As of February 2, 2026, Return On Tangible Assets is expected to decline to -0.21. In addition to that, Return On Capital Employed is expected to decline to -0.29. At present, Prothena Plc's Non Currrent Assets Other are projected to increase significantly based on the last few years of reporting. The current year's Other Assets is expected to grow to about 37.3 M, whereas Total Assets are forecasted to decline to about 427.3 M.
Last ReportedProjected for Next Year
Book Value Per Share 8.15  6.70 
Tangible Book Value Per Share 8.15  6.71 
Enterprise Value Over EBITDA(1.66)(1.75)
Price Book Value Ratio 1.76  1.67 
Enterprise Value Multiple(1.66)(1.75)
Price Fair Value 1.76  1.67 
Enterprise Value1.2 B618.2 M
Understanding the operational decisions made by Prothena Plc management offers insights into its financial robustness. This evaluation is crucial for assessing the stock's investment potential.
Operating Margin
(16.46)
Beta
(0.1)
Return On Assets
(0.29)
Return On Equity
(0.68)

Technical Drivers

As of the 2nd of February, Prothena Plc holds the Risk Adjusted Performance of (0.04), variance of 8.58, and Coefficient Of Variation of (1,431). Compared to fundamental indicators, the technical analysis model allows you to check existing technical drivers of Prothena Plc, as well as the relationship between them.

Prothena plc Price Movement Analysis

Execute Study
The output start index for this execution was twenty-three with a total number of output elements of thirty-eight. The Bollinger Bands is very popular indicator that was developed by John Bollinger. It consist of three lines. Prothena Plc middle band is a simple moving average of its typical price. The upper and lower bands are (N) standard deviations above and below the middle band. The bands widen and narrow when the volatility of the price is higher or lower, respectively. The upper and lower bands can also be interpreted as price targets for Prothena plc. When the price bounces off of the lower band and crosses the middle band, then the upper band becomes the price target.

Prothena plc Insider Trading Activities

Some recent studies suggest that insider trading raises the cost of capital for securities issuers and decreases overall economic growth. Trading by specific Prothena Plc insiders, such as employees or executives, is commonly permitted as long as it does not rely on Prothena Plc's material information that is not in the public domain. Local jurisdictions usually require such trading to be reported in order to monitor insider transactions. In many U.S. states, trading conducted by corporate officers, key employees, directors, or significant shareholders must be reported to the regulator or publicly disclosed, usually within a few business days of the trade. In these cases Prothena Plc insiders are required to file a Form 4 with the U.S. Securities and Exchange Commission (SEC) when buying or selling shares of their own companies.

Prothena Plc Outstanding Bonds

Prothena Plc issues bonds to finance its operations. Corporate bonds make up one of the largest components of the U.S. bond market, which is considered the world's largest securities market. Prothena plc uses the proceeds from bond sales for a wide variety of purposes, including financing ongoing mergers and acquisitions, buying new equipment, investing in research and development, buying back their own stock, paying dividends to shareholders, and even refinancing existing debt. Most Prothena bonds can be classified according to their maturity, which is the date when Prothena plc has to pay back the principal to investors. Maturities can be short-term, medium-term, or long-term (more than ten years). Longer-term bonds usually offer higher interest rates but may entail additional risks.

Prothena Plc Predictive Daily Indicators

Prothena Plc intraday indicators are useful technical analysis tools used by many experienced traders. Just like the conventional technical analysis, daily indicators help intraday investors to analyze the price movement with the timing of Prothena Plc stock daily movement. By combining multiple daily indicators into a single trading strategy, you can limit your risk while still earning strong returns on your managed positions.

Prothena Plc Corporate Filings

8K
12th of December 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
8K
19th of November 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
13A
14th of November 2025
An amended filing to the original Schedule 13G
ViewVerify
13A
12th of November 2025
An amended filing to the original Schedule 13G
ViewVerify
8K
6th of November 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
13A
17th of October 2025
An amended filing to the original Schedule 13G
ViewVerify
7th of October 2025
Other Reports
ViewVerify
25th of September 2025
Other Reports
ViewVerify

Prothena Plc Forecast Models

Prothena Plc's time-series forecasting models are one of many Prothena Plc's stock analysis techniques aimed at predicting future share value based on previously observed values. Time-series forecasting models ae widely used for non-stationary data. Non-stationary data are called the data whose statistical properties e.g. the mean and standard deviation are not constant over time but instead, these metrics vary over time. These non-stationary Prothena Plc's historical data is usually called time-series. Some empirical experimentation suggests that the statistical forecasting models outperform the models based exclusively on fundamental analysis to predict the direction of the market movement and maximize returns from investment trading.

Prothena Plc Bond Ratings

Prothena plc financial ratings play a critical role in determining how much Prothena Plc have to pay to access credit markets, i.e., the amount of interest on their issued debt. The threshold between investment-grade and speculative-grade ratings has important market implications for Prothena Plc's borrowing costs.
Piotroski F Score
4
PoorView
Beneish M Score
(3.94)
Unlikely ManipulatorView

Prothena plc Debt to Cash Allocation

As Prothena plc follows its natural business cycle, the capital allocation decisions will not magically go away. Prothena Plc's decision-makers have to determine if most of the cash flows will be poured back into or reinvested in the business, reserved for other projects beyond operational needs, or paid back to stakeholders and investors.
Prothena plc currently holds 10.84 M in liabilities with Debt to Equity (D/E) ratio of 0.02, which may suggest the company is not taking enough advantage from borrowing. Prothena plc has a current ratio of 12.74, suggesting that it is liquid enough and is able to pay its financial obligations when due. Note, when we think about Prothena Plc's use of debt, we should always consider it together with its cash and equity.

Prothena Plc Common Stock Shares Outstanding Over Time

Prothena Plc Assets Financed by Debt

The debt-to-assets ratio shows the degree to which Prothena Plc uses debt to finance its assets. It includes both long-term and short-term borrowings maturing within one year. It also includes both tangible and intangible assets, such as goodwill.

Prothena Plc Debt Ratio

    
  2.17   
It appears most of the Prothena Plc's assets are financed through equity. Typically, companies with high debt-to-asset ratios are said to be highly leveraged. The higher the ratio, the greater risk will be associated with the Prothena Plc's operation. In addition, a high debt-to-assets ratio may indicate a low borrowing capacity of Prothena Plc, which in turn will lower the firm's financial flexibility.

Prothena Plc Corporate Bonds Issued

Most Prothena bonds can be classified according to their maturity, which is the date when Prothena plc has to pay back the principal to investors. Maturities can be short-term, medium-term, or long-term (more than ten years). Longer-term bonds usually offer higher interest rates but may entail additional risks.

Prothena Net Debt

Net Debt

(435.22 Million)

At present, Prothena Plc's Net Debt is projected to decrease significantly based on the last few years of reporting.

About Prothena Stock Analysis

Stock analysis is the technique used by a trader or investor to examine and evaluate how Prothena Plc prices is reacting to, or reflecting on a current market direction and economic conditions. It can be used to make informed decisions about market timing, and when buying or selling Prothena shares will generate the highest return on investment. We also built our stock analysis module to help investors to gain an insight into the world economy as a whole, the stock market, thematic ideas. a specific sector, or an individual Stock such as Prothena Plc. By using and applying Prothena Stock analysis, traders can create a robust methodology for identifying Prothena entry and exit points for their positions.
Last ReportedProjected for Next Year
Pretax Profit Margin(0.86)(0.90)
Operating Profit Margin(1.03)(1.08)
Net Loss(0.81)(0.86)
Gross Profit Margin(99.81)(104.80)

Current Prothena Analysis - Recommendations

We track the performance of the top 100 financial experts across various large and mid-size financial boutiques. Prothena analyst recommendations are determined by taking all analyst recommendations and averaging them as Strong Buy, Buy, Hold, Strong Sell or Sell. There is no one specific way to measure analysis performance other than comparing it to the past results via a very sophisticated attribution analysis. Prothena analyst consensus and target price projections should be used in combination with other traditional techniques such as stock price forecasting, technical analysis, earnings estimate, and various momentum models.
Target PriceConsensus# of Analysts
20.33Strong Buy10Odds
Prothena plc current and past analyst recommendations published by a number of research institutions as well as average analyst consensus.
Most Prothena analysts issue ratings four times a year, at intervals of three months. Ratings are usually accompanied by a target price to helps potential investors understand Prothena stock's fair price compared to its market value. Analysts arrive at stock ratings after researching public financial statements of Prothena plc, talking to its executives and customers, or listening to Prothena conference calls.
Prothena Analyst Advice Details

Prothena Stock Analysis Indicators

Prothena plc stock analysis indicators help investors evaluate how Prothena Plc stock reacts to ongoing and evolving market conditions. The investors can use it to make informed decisions about market timing and determine when trading Prothena Plc shares will generate the highest return on investment. By understating and applying Prothena Plc stock analysis, traders can identify Prothena Plc position entry and exit signals to maximize returns.
Begin Period Cash Flow621 M
Common Stock Shares Outstanding53.8 M
Total Stockholder Equity486.9 M
Total Cashflows From Investing Activities-298 K
Tax Provision-6.6 M
Property Plant And Equipment Net13.8 M
Cash And Short Term Investments471.4 M
Cash471.4 M
Accounts Payable7.8 M
Net Debt-460.5 M
50 Day M A9.7872
Total Current Liabilities48.5 M
Other Operating Expenses289.7 M
Non Current Assets Total61.7 M
Forward Price Earnings10.8696
Non Currrent Assets Other3.8 M
Stock Based Compensation46 M

Complementary Tools for Prothena Stock analysis

When running Prothena Plc's price analysis, check to measure Prothena Plc's market volatility, profitability, liquidity, solvency, efficiency, growth potential, financial leverage, and other vital indicators. We have many different tools that can be utilized to determine how healthy Prothena Plc is operating at the current time. Most of Prothena Plc's value examination focuses on studying past and present price action to predict the probability of Prothena Plc's future price movements. You can analyze the entity against its peers and the financial market as a whole to determine factors that move Prothena Plc's price. Additionally, you may evaluate how the addition of Prothena Plc to your portfolios can decrease your overall portfolio volatility.
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